The modern stool test for the early detection of colorectal cancer

ColoAlert not only detects blood in stool like conventional stool tests, but also tumor-related DNA changes. This makes colorectal cancer visible in its early stages – discreetly, safely, and conveniently from home.

Every second diagnosis of colorectal cancer is made in late stages.

Every eight minutes, someone in Germany is diagnosed with colorectal cancer. If the disease is detected early, the chances of a cure are very good . Unfortunately, half of those affected only receive the diagnosis in an advanced stage. Reasons for this include the low uptake of colonoscopies and the limited detection rate of conventional stool tests.

  • If detected early, colon cancer is often curable.

  • Conventional stool tests are often too inaccurate.

  • Every second diagnosis is made in the late stage.

  • Reduced chances of recovery & more difficult therapy

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  • ColoAlert stool test
    order

  • Comfortable at home
    Take samples

  • Samples to us
    return

  • In a few days
    Results received

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Frequently Asked Questions

For whom is the ColoAlert stool test suitable as a preventative measure?

ColoAlert is generally suitable for people aged 45 and over. Public acceptance of preventive measures like the ColoAlert test is increasing, especially compared to occult blood tests (iFOBTs). In certain cases—for example, if additional risk factors are present—use may also be advisable outside this age range after consultation with a doctor.

However, ColoAlert is not suitable for people with irritable bowel syndrome, chronic inflammatory bowel diseases such as ulcerative colitis or Crohn's disease, as well as for those with familial adenomatous polyposis (FAP) or hereditary non-polyposis colorectal cancer (HNPCC).

What is the sample tested for in the laboratory during the ColoAlert stool test?

In addition to detecting occult blood, ColoAlert analyzes three further tumor markers. The molecular genetic analysis examines the stool sample for the presence of suspiciously high amounts of human DNA and genetic mutations. The diagnostics company Mainz Biomed develops and optimizes tests for the early detection of colorectal cancer to increase the efficiency and user-friendliness of screening tests. These additional features increase the detection rate for colorectal cancer, the so-called sensitivity (proportion of positive test results among those affected). Mainz Biomed specializes in cancer screening and offers innovative solutions for the early identification of cancers.

Has the ColoAlert stool test been subjected to clinical trials?

All measurement methods are subject to a certain error rate. In diagnostics, the error rate is represented by sensitivity (proportion of true positive results) and specificity (proportion of true negative results).

The sensitivity of the ColoAlert colorectal cancer test (Combined DNA stool assay) is 85% and the specificity is 92%, according to several independent clinical studies. Mainz Biomed, the company behind ColoAlert, developed the test with advanced features to optimize user-friendliness and screening efficiency. In one study, ColoAlert achieved better results in terms of sensitivity and specificity than the occult blood and M2-PK tests that were also evaluated.