Frau hält ein blaues Kärtchen in Form eines Darms vor sich

Colorectal Cancer Remains A Widespread Disease

Across Europe, colorectal cancer places a growing burden on patients, families, and health systems with more than 350,000 new cases diagnosed each year. When detected early, cure rates are high. Too often, diagnosis happens late, reducing the chance of cure and increasing the complexity of care. Prevention and early detection help limit disease progression and protect quality of life.

  • >350,000

    New Cases Per Year

  • 50%

    of Diagnoses In Late Stages

  • 15%

    Survival Rate In Stage IV

Offer Your Patients More Precise, Non Invasive Colorectal Cancer Screening

ColoAlert is the next step in colorectal cancer screening. Unlike a FIT (faecal immunochemical test), ColoAlert detects not only blood in stool but also tumour DNA. This supports a higher detection rate, particularly in early stages where treatment outcomes are often best.¹˒² The test is simple to use at home and easy to integrate into daily life. Your practice gains a practical tool to strengthen preventive care and patient guidance.

  • Detects Colon Cancer & Adenomas¹

  • High Specificity Through Direct Tumor Markers¹

  • Convenient At-Home Screening

1 3

ColoAlert Is the Stool Test That Takes a Closer Look

FIT

(conventional stool test)
68 %²
Detection rate
65 %²
Detection rate in early stages (0/I/II)
Occult Blood
Examined Markers
Every 2 Years
Testing Interval

ColoAlert

(DNA-based stool test)
85 %¹
Detection rate
80 %¹
Detection rate in early stages (0/I/II)
Occult Blood
Mutated DNA
hDNA
Examined Markers
Every 3 Years
Testing Interval

For Which Patients Is ColoAlert Suitable?

We recommend ColoAlert screening every three years for everyone aged 50 and over. For people with a first degree family history of colorectal cancer, screening should start from age 40, as early onset colorectal cancer is becoming more frequent.

What Symptoms Should I Look Out For In Patients?

Colorectal cancer often develops without noticeable symptoms. Possible signs include changes in bowel habits such as frequent diarrhoea or constipation, rectal bleeding or blood in stool, and persistent abdominal discomfort including cramps, bloating, or pain. A feeling of incomplete bowel emptying, unexplained weakness or fatigue, and unintentional weight loss can also be indicators.⁴

What Are The Recommended Actions In The Event Of A Positive Test Result?

If a ColoAlert test is positive, the next step should be colonoscopy to confirm findings and remove any lesions. If no abnormalities are detected, a follow up colonoscopy within one year is recommended, as early lesions can be missed due to preparation quality or anatomical factors.

Order ColoAlert For Your Practice


As a physician, you play a key role in colorectal cancer prevention. ColoAlert is an innovative stool test that offers patients convenient and precise screening. Complete the order form to trial ColoAlert in your practice.

Order Practice Set

References

1) Krammes, L., Mahmood, HA, Frondorf, FMB, Scholz, CF, Becker, P., Maharjan, S., Sever, AE, Garapati, SV, Balasubramaniam, A., Knabe, MJ, Eidens, MR, Dollinger, MM (2025). State-of-the-Art Colorectal Cancer and Advanced Precancerous Lesion Screening: a Multitarget Stool DNA Test, Clinical Laboratory, 71(1), 34-39. doi.org/10.7754/Clin.Lab.2024.240620 ; Dollinger, MM, Behl, S., & Fleig, WE (2018). Early Detection of Colorectal Cancer: a Multi-Center Pre-Clinical Case Cohort Study for Validation of a Combined DNA Stool Test. Clinical Laboratory, 64(10), 1719-1730. doi.org/10.7754/Clin.Lab.2018.18052 2) Gies, A., Cuk, K., Schrotz-King, P., & Brenner, H. (2018). Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening. Gastroenterology, 154(1), 93–104. doi.org/10.1053/j.gastro.2017.09.018 3) Robert Koch Institute and the Association of Population-Based Cancer Registries in Germany (2023). Cancer in Germany for 2019/2020, 14th edition. 4) German Cancer Research Center (2022). Colorectal cancer: Symptoms and warning signs. [https://www.krebsinformationsdienst.de/tumorarten/darmkrebs/symptome.php, accessed March 7, 2023]